Applications

Picture: Bone in a distal femur
Courtesy of Duncan Bassett, Alan Boyde and Graham Williams, Molecular Endocrinology Laboratory, Imperial College London

Biomedical engineering

TESCAN SEMs combine the latest concepts from medicine, biotechnology and engineering for designing a variety of technologies such as support matrices for cell growth, artificial tissue and implantable biomedical device.

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Cell & Tissue morphology

TESCAN MIRA3 and MAIA3 FEG-SEMs are the ideal instruments for investigating cellular and tissue structure with high resolution. Typical applications involve observing shape changes of grooves, pores, blebs or microvilli on the cellular in response to the changes in the extracellular environment.

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Microbiology

High resolution imaging of the microbial surface using SEM helps to have a better understanding of the morphology of microbial populations, bacteria communication and biofilm formation. TESCAN SEMs help researchers visualize microbial populations with great focal depth and high resolution.

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Pharmaceuticals

TESCAN SEMs offer very high resolution imaging and superb analytical performance, which make them perfect and reliable tools for quality control of new preparations. Our dedicated EasySEM and EasyEDX software options transform our systems into easy-to-use instruments for routine quality control.

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Plant and animal biology

High resolution and large depth of focus are features which make SEM a suitable method for observing topography of biological samples. A large variability of TESCAN SEMs can fulfill any customers’ needs.

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Subcellular analysis

The SEM technology is becoming more popular in this field, due to emerging techniques which are available to scanning electron microscopy. TESCAN offers several solutions for scientists interested in the subcellular investigations of biological samples.

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Environmental and Food Sciences

Electron microscopy has been an irreplaceable tool for studying many environmental systems. TESCAN SEMs portfolio covers a variety of instruments and analytical solutions for analyzing pollution particles, water and soil organisms, minerals, rocks, crops, and many more.

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Techniques

Picture: Tube building mechanism
Courtesy of James C. Weaver, Wyss Institute, Harvard University

Correlative microscopy

Fluorescence microscopy is well suited for the localization of areas of interest either in fixed or live cells, which are visualized by fluorescence labeling with chemical probes, antibodies or genetic tags. Such labeling can navigate scientists to the important areas such as active sites on the cellular surface of rare cell populations.

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FIB-SEM - Focused ion beam scanning electron microscopy

Focused ion beam scanning electron microscopy (FIB-SEM) combines two beams (electron and ion) in one instrument. The SEM column provides high resolution imaging, while the FIB column mills the observed sample.

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Cryogenic techniques

All TESCAN SEMs can be equipped with a variety of cryo-processing tools from the major vendors. This allows researchers to take full advantage of all our imaging capabilities with the state-of-the-art cryo technology of their choice.

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Low Vacuum Scanning Electron Microscopy

Low vacuum or environmental scanning electron microscopy have been commonly used techniques applied to highly charging samples or samples with high amount of water.

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Scanning transmission electron microscopy

Every TESCAN SEM can be easily transformed into a low-kV range STEM instrument by adding dedicated STEM detectors inside the SEM chamber. The bright and dark field imaging modes can be collected simultaneously together with the SE and BSE signals and other analytical techniques, such as EDX.

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